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Matrix
- 3-Dimensional Structure
- High Porosity
- High surface area to volume ration-
- available growth area 60-70 cm2/ml
- Excellent biocompatibility
- inert metal composite
- clinical product is FDA compliant*
- Fully interconnected geometry
- Surface coatable
- antibodies, adhesion molecules etc.
- Multiple configurations
- 6, 12, 24, 48, 96 well units and 30 x 60mm format
- Scalable Technology
*Clinical product is not for commercial sale
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- High Density growth
- 2 x 107 to 8 x 107 cells/ml attainable
- tissue-like density
- Variety of applications and configurations
- basic research
- bioproduction
- protein/expressed product
- cell mass
- drug candidate screening
- Theranostics/Diapeutics
- co-culture systems
- Pilot scale, custom assemblies
- Successful culture of:
- primary cells; hepatocytes, fibroblasts, mesenchymal,
islet and neuronal cells
- transformed cells: cancer cells and lines
- production cells: CHO, 3T3, and HEK 293 cells
- No dead space in growth area
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Scanning electron micrographs of Cytomatrix™
Advantages
- Uniform 3-Dimensional Structure
- The 3-Dimensional structure and porosity of the Cytomatrix™
bears a remarkable resemblance of that of human bone marrow trebeculae.
This provides cells with an in vivo,
tissue-like cellular growth scaffold for a variety of cell culture
applications.
- Unique Textured Surface
- The Cyotmatrix™ inert metallic coating provides the cells
with a novel, highly textured surface to which attachment-dependent
cells have a remarkable affinity for attachment and growth. This
provides the cells with a desirable substrate on which to adhere
and thrive.
- Biomimetic Microenvironment
- The unique 3-Dimensional architecture of the Cytomatrix™
is a highly desirable structure with in situ-like
properties. This provides attachment-dependent cells with a biomimetic
microenvironment, which fosters natural inter-cellular signaling
and simulates growth in an in vivo,
tissue-like setting.
- Versatile
- The reliability of the highly consistent architecture of the
Cytomatrix™ allows for a wide variety of product formats
and presentations. This provides the end-user with a highly versatile
research tool to investigate a wide variety of cell culture applications.
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Tuning Fork Assembly
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Features
- 1-4 similar sized units in each assembly
- Integrated handle
- Sterilized
- Disposable
- Culture evaluation
- In situ microscopy
- Bright field
- Fluorescent
- Electron
- Confocal
- Cell Isolation
- Vital staining
- Biomass Production
- Cell enumeration
- Dye staining
- Vital
- Crystal violet
- Immunofluorescence
- Co-culture studies
- Cell adhesion
- Cell signaling
- Cell extracts
- Western blots
- Northern blots
- Reporter Assays
- DNA isolation
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Benefits
- Units designed for processing in various sized multi-wells
- Facilitates aeseptic assembly
- Ready-to-use
- Convenient, easy clean-up
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Cytomatrix™ Tuning Fork Assembly
30mm - left
9mm - right
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9mm Tuning Fork Assembly with 2 discs removed for
sampling
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